Induction of morphological aberrations by enzyme inhibition inDrosophila melanogaster
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چکیده
منابع مشابه
Enzyme induction and inhibition.
The rate and extent of drug metabolism significantly influences drug effect. Enzyme induction by increasing the metabolism of drugs may result in important drug interactions. Other implications of enzyme induction include alterations in the metabolism of endogenous substrates, vitamins and activity of extrahepatic enzyme systems. Similarly a wide range of drugs may produce clinically significan...
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Among various systems in which induction of new enzyme synthesis can be initiated, that developed by Talalay,'-3 in which the metabolism of a variety of steroids by Pseudomonas testosieroni is induced by either testosterone or certain other steroidal compounds, has been particularly rewarding. Recent studies of this system by Wacker et al.4' 5 have suggested that a complex may be formed between...
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Administration of phenobarbital or 3-methylcholanthrene to animals markedly enhances the activity of several reduced triphosphopyridine nucleotide-dependent enzyme systems in liver microsomes (l-5). Although the resistance of these enzyme systems to solubihzation and purification has prevented definitive studies on the mechanism by which the enhanced activity occurs, such as has been done with ...
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Studies on several gram-negative bacteria grown on certain individual amino acids, and indicate that the cell envelopes of such organisms are described in the present communication. contain a relatively large number of amino acids (Salton, 1956). It might reasonably be expected MATERIALS AND METHODS that interference with the synthesis, or limitation Cultures of R. rubrum (strain Si) were grown...
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ژورنال
عنوان ژورنال: Experientia
سال: 1969
ISSN: 0014-4754,1420-9071
DOI: 10.1007/bf01897891